PtoDC3000 produces Cys protease inhibitor Cip1!
Pseudomonas syringae pv. tomato DC3000 (PtoDC3000) produces an inhibitor targeting secreted Cys proteases of its host, tomato. We coined this chagasin-like inhibitor Cip1 and it evades recognition by the Rcr3/Cf-2 system, possibly by its low affinity for Rcr3. This is the fourth unrelated pathogen-derived inhibitor targeting the same secreted Cys proteases of the host. Previously identified inhibitors were from a tomato-pathogenic fungus (Avr2), oomycete (EpiCs) and nematode (Vap1). Click here for more information.